Aerobic exercise in your twenties can keep you mentally fit and protect memory in middle age. According to a new study activities that maintain cardio fitness- such as running, swimming and cycling lead to better thinking skills and memory 20 years on, according to researchers at the University of Minnesota, Minneapolis. Researchers tested almost 3,000 healthy people with an average age of 25. They underwent treadmill tests of cardiovascular fitness during the first year of the study and again 20 years later.